Saliva Testing

Saliva testing is a convenient, inexpensive, and above all, accurate means of testing steroid hormones. Scientific studies have shown a strong correlation between steroid hormone levels in saliva and the amount of hormone in the blood that is active or "bioavailable." Saliva is an ideal diagnostic medium to measure the bioavailable levels of steroid hormones active in the tissue. It is this fraction of total hormone that is free to enter the target tissues in the brain, uterus, skin, and breasts.

Saliva testing can be done anywhere anytime. Testing that relies on blood drawn in the doctor's office makes it harder to obtain samples at specific times (such as in the early morning) or multiple times during the day. In addition, hormones in saliva are exceptionally stable and can be stored at room temperature for up to a week without affecting the accuracy of the result. This offers maximum flexibility in sample collection and shipment.
Best ValueBlood Spot and Saliva Tests are also available in ZRT's Combo Test Kit. Learn More
Hormones Tested in Saliva
Hormones we test in saliva include:

  • Estradiol (E2)
  • Estrone (E1)
  • Estriol (E3)
  • Progesterone (pg)
  • Testosterone (T)
  • DHEA-S (Ds)
  • Cortisol (C)

Reference and supplementation ranges:
- Saliva Reference Ranges
- Observed Salivary Supplementation Ranges
- ZRT Reference Range Determination
Profiles in Saliva
Profiles we offer in saliva include:

  • Female/Male Saliva Profile I
    (E2, Pg, T, DS, & C)
  • Female/Male Saliva Profile II
    (E2, Pg, T, DS, & C x 2)
  • Female/Male Saliva Profile III
    (E2, Pg, T, DS, & C x 4)

Compare Saliva and Blood Spot
The following table compares which tests are done in saliva and/or blood spot.
 

Hormone or Analyte

Saliva

Blood Spot

Estradiol (E2)

Progesterone (Pg)

Testosterone, free

 

Testsoterone, total

 

DHEA-S (DS)

Cortisol, AM (C1)

Cortisol, Diurnal (C1, C2, C3, C4)

 

Estriol (E3)

 

Estrone (E1)

 

Follicle stimulating hormone (FSH)

 

Lutenizing Hormone (LH)

 

Insulin-like Growth Factor (IGF-1)

 

Insulin, fasting

 

Triglycerides (TG)

 

Hemoglobin A1C (HbA1c)

 

High Sensitivity C-Reactive Protein (hs-CRP)

 

Total Cholesterol (CH)

 

LDL Cholesterol

 

HDL Cholesterol

 

VLDL Cholesterol

 

Prostate specific antigen (PSA)

 

Sex hormone binding globulin (SHBG)

 

Thyroid peroxidase antibodies (TPO)

 

Thyroid stimulating hormone (TSH)

 

Triiodothyronine (T3), free

 

Thyroxine (T4), free

 

25-hydroxy vitamin D2

 

25-hydroxy vitamin D3